make a big profit; often in a short period of time
The investor really cleaned up when the stock market went up
dispose of
settle the bills
make oneself clean, presentable or neat
Clean up before you go to the party
English Idioms Dictionary
make a lot of money, make a big profit I cleaned up at the horse races last year and still have some of the money left.
Bloomberg Financial Glossary
In the context of general equities, purchase/sale of all the remaining supply of stock, or the last piece of a block, in a trade-leaving a net zero position.
